Pemetrexed Disodium and Von Willebrand factor recombinant

• Generic Name: pemetrexed
• Dosage Forms: n.a.
• Other Brand Names: Alimta

Used in combination with cisplatin for the treatment of malignant pleural mesothelioma in adults whose disease is unresectable or who otherwise are not candidates for potentially curative surgery (designated an orphan drug by FDA for this indication).

Monotherapy for the treatment of locally advanced or metastatic non-small cell lung cancer in adults who have received prior chemotherapy. Efficacy based on surrogate end points of tumor response rate; improvement in disease-related symptoms or increased survival not demonstrated in clinical studies.

• Generic Name: von willebrand factor
• Dosage Forms: n.a.
• Other Brand Names: Vonvendi, Wilfactin

Von Willebrand factor is a naturally occurring protein in the blood that helps blood to clot. People with an inherited blood-clotting disorder called von Willebrand disease do not have enough of this protein in their blood. A lack of von Willebrand factor can cause uncontrolled bleeding.

Von Willebrand factor is used to control bleeding episodes in adults with von Willebrand disease.

Von Willebrand factor may also be used for purposes not listed in this medication guide.