Pemetrexed Disodium and Xtandi

• Generic Name: pemetrexed
• Dosage Forms: n.a.
• Other Brand Names: Alimta

Used in combination with cisplatin for the treatment of malignant pleural mesothelioma in adults whose disease is unresectable or who otherwise are not candidates for potentially curative surgery (designated an orphan drug by FDA for this indication).

Monotherapy for the treatment of locally advanced or metastatic non-small cell lung cancer in adults who have received prior chemotherapy. Efficacy based on surrogate end points of tumor response rate; improvement in disease-related symptoms or increased survival not demonstrated in clinical studies.

• Generic Name: enzalutamide
• Dosage Forms: capsule
• Other Brand Names: Xtandi

Xtandi (enzalutamide) is an anti-androgen. It works in the body by preventing the actions of androgens (male hormones).

Xtandi is used to treat prostate cancer.

Xtandi may also be used for purposes not listed in this medication guide.