Pentazocine and Naloxone and Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln
Determining the interaction of Pentazocine and Naloxone and Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:The following interaction applies only if you are using naloxone in an injectable formulation: naloxone can reverse the effects of pentazocine. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: This warning does not apply to the naloxone component in non-injectable formulations of naloxone-containing combination medicines. Naloxone injection is an antagonist that will reverse the actions of opiates. This reversal can occur when the opiate drug is being used clinically and when it is being abused. Physically dependent patients may experience withdrawal symptoms. Abrupt postoperative opioid reversal has resulted in hypotension, ventricular tachycardia and fibrillation, pulmonary edema, cardiac arrest, encephalopathy, and death.
MANAGEMENT: Patients receiving naloxone injection should be monitored for changes in vital signs, nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, abdominal cramps.
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- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Narcan (naloxone)." DuPont Pharmaceuticals, Wilmington, DE.
Generic Name: naloxone / pentazocine
Brand name: Talwin NX
Synonyms: Naloxone and pentazocine
Generic Name: polyethylene glycol 3350 with electrolytes
Brand name: Colyte with Flavor Packs, GaviLyte-C, GoLYTELY, MoviPrep, NuLYTELY Orange, NuLYTELY with Flavor Packs, PEG-3350 with Electolytes, Plenvu, TriLyte with Flavor Packs, NuLYTELY, TriLyte, Suclear
Synonyms: Polyethylene glycol electrolyte solution, Polyethylene Glycol-Electrolyte Solution
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Aqueous Gel
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Cleanser
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Cream
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Foam
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Lotion
- Pentazocine and Naloxone-Sodium Sulfacetamide and Sulfur Suspension
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentazocine Hydrochloride
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentazocine Injection
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentazocine Lactate
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentetate
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentetate Calcium Trisodium
- Sodium Sulf/Potassium Sulf/Mag Sulf/Polyethylene Glycol-Electrolyte Soln-Pentetate calcium trisodium Intravenous, Inhalation, oral/nebulization