Pentazocine Hydrochloride and Voltaren
Determining the interaction of Pentazocine Hydrochloride and Voltaren and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using pentazocine together with diclofenac may cause seizures. Contact your doctor if you experience tremors, involuntary muscle movements, and seizures. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Grand mal seizures following a single diclofenac dose have been reported in a patient on long-term pentazocine therapy. Seizures recurred upon inadvertent rechallenge with diclofenac. The role pentazocine played in this case remains to be determined. However, pentazocine is known to reduce the seizure threshold.
MANAGEMENT: Patients receiving this combination should be monitored for increased CNS stimulation (tremors, involuntary muscle movements, seizures) and should be advised to notify their physician if they experience such symptoms.
- Heim M, Nadvorna H, Azaria M "Grand mal seizures following treatment with diclofenac and pentazocine." S Afr Med J 78 (1990): 700-1
Generic Name: pentazocine
Brand name: Talwin
Synonyms: Pentazocine
Generic Name: diclofenac
Brand name: Voltaren, Voltaren-XR, also Cambia, Cataflam, Zipsor, Zorvolex, Dyloject, Cambia
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pentazocine Hydrochloride-Voltaren Gel
- Pentazocine Hydrochloride-Voltaren Ophtha
- Pentazocine Hydrochloride-Voltaren Ophthalmic
- Pentazocine Hydrochloride-Voltaren Topical
- Pentazocine Hydrochloride-Voltaren-XR
- Pentazocine Hydrochloride-Von Willebrand Factor
- Voltaren-Pentazocine Injection
- Voltaren-Pentazocine Lactate
- Voltaren-Pentetate
- Voltaren-Pentetate Calcium Trisodium
- Voltaren-Pentetate calcium trisodium Intravenous, Inhalation, oral/nebulization
- Voltaren-Pentetate Indium Disodium In 111