Pentobarbital Sodium and Pyridoxine
Determining the interaction of Pentobarbital Sodium and Pyridoxine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:One small study has suggested that pyridoxine may decrease serum levels of phenobarbital. The mechanism is unknown. Phenobarbital is the only barbiturate specifically implicated in this interaction. However, other barbiturates may behave in a similar fashion. Close observation for altered barbiturate effects is indicated if these drugs must be used together.
- Hansson O, Sillanpaa M "Pyridoxine and serum concentration of phenytoin and phenobarbitone." Lancet 1 (1976): 256
Generic Name: pentobarbital
Brand name: Nembutal Sodium, Nembutal
Synonyms: Pentobarbital (injection), PENTobarbital
Generic Name: pyridoxine
Brand name: Vitamin B6, Vitelle Nestrex, Pyridoxal 5'-Phosphate
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pentobarbital Sodium-Pyridoxine (Vitamin B6) Capsules and Tablets
- Pentobarbital Sodium-Pyridoxine (Vitamin B6) Extended-Release Tablets
- Pentobarbital Sodium-Pyridoxine (Vitamin B6) Injection
- Pentobarbital Sodium-Pyridoxine Hydrochloride
- Pentobarbital Sodium-Pyridoxine Hydrochloride Injection
- Pentobarbital Sodium-Pyridoxine Oral, Injection
- Pyridoxine-Pentobarbital Sodium Injection
- Pyridoxine-Pentopak
- Pyridoxine-Pentosan polysulfate sodium
- Pyridoxine-Pentostatin
- Pyridoxine-Pentostatin Intravenous
- Pyridoxine-Pentothal