Pentobarbital Sodium and Zidovudine Intravenous

• Generic Name: pentobarbital
• Dosage Forms: n.a.
• Other Brand Names:

  Nembutal Sodium, Nembutal

Short-term treatment of insomnia (i.e., ≤2 weeks duration); decreased effectiveness for sleep induction and maintenance after 2 weeks.

Has been used for routine sedation. However, barbiturates used infrequently for this indication since there are few clinical situations in which oral barbiturates provide a safety or efficacy advantage over nonbarbiturate sedatives/hypnotics.

Preoperatively, to produce sedation and relieve anxiety.

Provide basal hypnosis for general, spinal, or regional anesthesia, or to facilitate intubation procedures.

Alternate therapy to control status epilepticus or acute seizure episodes resulting from meningitis, poisons, eclampsia, alcohol withdrawal, tetanus, or chorea.

IV diazepam generally considered drug of choice for termination of status epilepticus.

Withdrawal of barbiturate or nonbarbiturate hypnotics in physically dependent patients.

Has been used to control acute episodes of agitated behavior in psychoses; however, little value in long-term management of psychoses.

Has been used in high doses to induce coma in the management of cerebral ischemia and increased intracranial pressure associated with head trauma, stroke, Reye’s syndrome, cardiac arrest, asphyxiation, or drowning.

Has been used to ameliorate or prevent sequelae associated with cerebral ischemia during neurosurgical procedures that require long periods of cerebral hypoxia.

• Generic Name: zidovudine
• Dosage Forms: n.a.
• Other Brand Names: Retrovir

Zidovudine (also known as AZT) injection is used together with other medicines for the treatment of the infection caused by the human immunodeficiency virus (HIV). HIV is the virus that causes acquired immune deficiency syndrome (AIDS). Zidovudine injection is used to slow the progression of disease in patients infected with HIV who have advanced symptoms, early symptoms, or no symptoms at all. Zidovudine is also used to help prevent pregnant women who have HIV from passing the virus to their babies during pregnancy and at birth.

Zidovudine injection will not cure or prevent HIV infection or AIDS, however, it helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems that usually result from AIDS or HIV disease. Zidovudine injection will not keep you from spreading HIV to other people. People who receive zidovudine may continue to have the problems usually related to AIDS or HIV disease.

Zidovudine is to be given only by or under the direct supervision of your doctor.