Pentostatin Intravenous and Rapamune (Sirolimus Tablets)

• Generic Name: pentostatin
• Dosage Forms: n.a.
• Other Brand Names: Nipent

Pentostatin belongs to the group of medicines called antimetabolites. It is used to treat a type of cancer of the white blood cells called hairy cell leukemia. Pentostatin may be used in patients with hairy cell leukemia who have already been treated with other medicines (e.g., alpha-interferon) that did not work well.

Pentostatin interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by pentostatin, other effects may also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with pentostatin, you and your doctor should talk about the good pentostatin will do as well as the risks of using it.

Pentostatin is to be administered only by or under the immediate supervision of your doctor.

• Generic Name: sirolimus
• Dosage Forms: oral solution, tablets
• Other Brand Names: Rapamune

• It is used after a kidney transplant to keep the body from rejecting the kidney.
• It is used to treat a lung disease called lymphangioleiomyomatosis (LAM).
• It may be given to you for other reasons. Talk with the doctor.