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Pentothal and Truxazole

Determining the interaction of Pentothal and Truxazole and the possibility of their joint administration.

Check result:
Pentothal <> Truxazole
Relevance: 05.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Sulfisoxazole may enhance and prolong the effects of thiopental. The mechanism is not fully understood. Reductions in thiopental dosage may be necessary.

References
  • Csogor SI, Papp J "Competition between sulphonamides and thiopental for the binding sites of plasma proteins." Arzneimittelforschung 20 (1970): 1925-7
Pentothal

Generic Name: thiopental

Brand name:

Synonyms: n.a.

Truxazole

Generic Name: sulfisoxazole

Brand name:

Synonyms: Truxazole (Oral)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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