Pepcid Oral Suspension and Viracept (Nelfinavir Tablets)
Determining the interaction of Pepcid Oral Suspension and Viracept (Nelfinavir Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:There is currently no information in the medical literature regarding a potential interaction between nelfinavir and H2-receptor antagonists. Nelfinavir peak plasma concentration (Cmax), systemic exposure (AUC) and trough plasma concentration (Cmin) decreased by 37%, 36% and 39%, respectively, when nelfinavir (1250 mg twice daily) was coadministered with omeprazole (40 mg once daily 30 minutes before nelfinavir) for 4 days, presumably due to decreased solubility of nelfinavir as gastric pH increased. Although theoretically possible, it is not certain to what extent such an interaction may occur with H2-receptor antagonists, or whether it is clinically relevant. Caution may be advisable during coadministration.
- "Product Information. Viracept (nelfinavir)." Agouron Pharma Inc, La Jolla, CA.
Generic Name: famotidine
Brand name: Pepcid Oral Suspension, Pepcid, Heartburn Relief, Pepcid AC, Pepcid AC Maximum Strength, Pepcid AC Chewable Tablets
Synonyms: n.a.
Generic Name: nelfinavir
Brand name: Viracept
Synonyms: Viracept
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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