Perampanel Tablets and Posaconazole Tablets
Determining the interaction of Perampanel Tablets and Posaconazole Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with potent inhibitors of CYP450 3A4 may increase the plasma concentrations of perampanel, which is primarily metabolized by the isoenzyme. In a clinical study, ketoconazole 400 mg daily for 10 days resulted in an increase in perampanel AUC by 20% and half-life by 15%. The clinical significance is unknown.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
Generic Name: perampanel
Brand name: Fycompa
Synonyms: Perampanel
Generic Name: posaconazole
Brand name: Noxafil
Synonyms: Posaconazole, Posaconazole (oral/injection)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Perampanel Tablets-PosiFlush flush
- Perampanel Tablets-Positive Skin Test Control - Histamine
- Perampanel Tablets-Posture
- Perampanel Tablets-Potaba
- Perampanel Tablets-Potaba (Potassium P-Aminobenzoate Capsules)
- Perampanel Tablets-Potaba (Potassium P-Aminobenzoate Powder)
- Posaconazole Tablets-Peranex HC
- Posaconazole Tablets-Percocet
- Posaconazole Tablets-Percocet 10/325
- Posaconazole Tablets-Percocet 2.5/325
- Posaconazole Tablets-Percocet 5/325
- Posaconazole Tablets-Percocet 7.5/325