Phenelzine Sulfate and Tylenol Sinus Congestion/Pain (Acetaminophen and Phenylephrine Tablets)
Determining the interaction of Phenelzine Sulfate and Tylenol Sinus Congestion/Pain (Acetaminophen and Phenylephrine Tablets) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenelzine together with phenylephrine is not recommended. Combining these medications can cause dangerously high blood pressure and even death. You may use phenylephrine only after you have been off phenelzine for at least 14 days. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting during treatment with phenelzine, as these may be signs and symptoms of excessively high blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:CONTRAINDICATED: Indirect- or mixed-acting sympathomimetic amines may precipitate severe hypertensive reactions and hyperpyrexia in patients treated with monoamine oxidase inhibitors (MAOIs). Death has occurred in some reported cases. The mechanism involves a synergistic sympathomimetic effect due to enhanced norepinephrine storage in adrenergic neurons (MAOI activity) and increased liberation of catecholamines (indirect sympathomimetic activity). Although the interaction has primarily involved nonselective MAOIs, hypertensive crisis has been reported in a patient taking ephedrine with the recommended dosage of a selective MAO-B inhibitor.
MANAGEMENT: In general, indirect- and mixed-acting sympathomimetic agents should not be used concurrently with MAOIs or other agents that possess MAOI activity (e.g., furazolidone, methylene blue, procarbazine). At least 14 days should elapse between discontinuation of MAOI therapy and initiation of treatment with sympathomimetic agents.
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Generic Name: phenelzine
Brand name: Nardil
Synonyms: Phenelzine
Generic Name: acetaminophen / phenylephrine
Brand name: Alka-Seltzer Plus Cold and Sinus, Contac Cold+Flu Non-Drowsy, Excedrin Sinus Headache Caplet, Mapap Sinus Congestion and Pain, QlearQuil Daytime Sinus & Congestion, Robitussin Nasal Relief, Sinus Congestion and Pain Daytime Cool Ice, Sinus Pain & Pressure, Sudafed PE Sinus Headache, Theraflu Daytime Severe Cold, Tylenol Sinus Congestion and Pain, Congespirin Aspirin Free, Neo Citran Extra Strength Cold and Sinus, Mapap Sinus PE, Tylenol Sinus Congestion Daytime, Excedrin Sinus Headache, Non-Pseudo Sinus Pain & Pressure, Robitussin Peak Cold Nasal Relief, Sudafed PE Pressure Plus Pain, Contact Cold and Flu Day, Tylenol Sinus + Headache Day, Vicks Sinex Daytime, Mygrex, Acetaminophen Congestion and Pain, QlearQuil Sinus & Congestion, Vicks DayQuil Sinex
Synonyms: Tylenol Sinus Congestion and Pain
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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