Phenergan VC and Treprostinil Injection Solution
Determining the interaction of Phenergan VC and Treprostinil Injection Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using phenylephrine together with treprostinil. Using these medications together can make treprostinil less effective. You should be counseled to consult with your doctor before taking over-the-counter decongestants. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Concurrent administration of decongestants or vasoconstrictors may negate the vasodilatory effects of prostacyclin analogs in patients with pulmonary hypertension.
MANAGEMENT: The use of decongestants and vasoconstrictors should probably be avoided in patients with pulmonary hypertension. Patients should be counseled to consult with their physician before taking over-the-counter decongestants such as phenylephrine and pseudoephedrine.
- Hardman JG, Gilman AG, Limbird LE eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 9th ed." New York, NY: McGraw-Hill (1995):
- "Product Information. Remodulin (treprostinil)." United Therapeutics Corp, Silver Spring, MD.
- "Product Information. Flolan (epoprostenol)." Glaxo Wellcome, Research Triangle Park, NC.
Generic Name: phenylephrine / promethazine
Brand name: Phenergan VC, Promethazine VC Plain, Promethazine VC
Synonyms: n.a.
Generic Name: treprostinil
Brand name: Orenitram, Remodulin, Tyvaso, Tyvaso Refill Kit, Tyvaso Starter Kit
Synonyms: Treprostinil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Phenergan VC-Treprostinil Oral Inhalation Solution
- Phenergan VC-Treprostinil Sodium
- Phenergan VC-Tresiba
- Phenergan VC-Tresiba FlexTouch
- Phenergan VC-Tresiba FlexTouch (Insulin Degludec (U-100) Prefilled Pens)
- Phenergan VC-Tresiba FlexTouch (Insulin Degludec (U-200) Prefilled Pens)
- Treprostinil Injection Solution-Phenergan w/Codeine
- Treprostinil Injection Solution-Phenobarbital
- Treprostinil Injection Solution-Phenobarbital Elixir
- Treprostinil Injection Solution-Phenobarbital Injection
- Treprostinil Injection Solution-Phenobarbital Oral Solution
- Treprostinil Injection Solution-Phenobarbital Sodium