Phenobarbital Injection and Sustol

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

In a human pharmacokinetic study, hepatic enzyme induction with phenobarbital resulted in a 25% increase in total plasma clearance of intravenous granisetron. Given the wide margin of safety of granisetron, the clinical significance of this change is unknown.

Phenobarbital Injection

Generic Name: phenobarbital

Brand name: Solfoton, Luminal

Synonyms: Phenobarbital, PHENobarbital

What is Phenobarbital Injection?

Sustol

Generic Name: granisetron

Brand name: Sustol, Kytril, Sancuso

Synonyms: Sustol (injection), Sustol Injection

What is Sustol?