Phentermine and topiramate and Warfarin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Coadministration with topiramate may decrease the anticoagulant effects of vitamin K antagonists (VKAs). The mechanism has not been delineated. MANAGEMENT: Until more information is available, patients receiving VKAs with topiramate should be closely monitored during concomitant therapy. The prothrombin time (PT) or International Normalized Ratio (INR) should be checked frequently and the VKA dosage adjusted accordingly, particularly following initiation, change of dosage, or discontinuation of topiramate therapy. References Cerner Multum, Inc. "Australian Product Information." O 0 Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

MONITOR: Coadministration with topiramate may decrease the anticoagulant effects of vitamin K antagonists (VKAs). The mechanism has not been delineated.

MANAGEMENT: Until more information is available, patients receiving VKAs with topiramate should be closely monitored during concomitant therapy. The prothrombin time (PT) or International Normalized Ratio (INR) should be checked frequently and the VKA dosage adjusted accordingly, particularly following initiation, change of dosage, or discontinuation of topiramate therapy.

Phentermine and topiramate

Generic Name: phentermine / topiramate

Brand name: Qsymia

Synonyms: Phentermine and Topiramate

What is Phentermine and topiramate?

Warfarin

Generic Name: warfarin

Brand name: Coumadin, Jantoven

Synonyms: n.a.

What is Warfarin?