Phenytek and Zovirax (Acyclovir Suspension)

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Before taking phenytoin, tell your doctor if you also use acyclovir. You may need dose adjustments or special tests in order to safely take both medications together. This combination may affect phenytoin levels in your body. You should notify your doctor if your seizure control changes or worsens. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

MONITOR: A case report suggests that plasma phenytoin concentrations may be decreased in the presence of acyclovir. Seizure activity may increase. The mechanism is unknown. A similar interaction may theoretically occur with other hydantoins.

MANAGEMENT: The clinician should consider closer clinical and laboratory monitoring if acyclovir therapy is started or stopped in the presence of phenytoin. The dose of phenytoin should be adjusted as clinically indicated. Patients should be advised to report loss of seizure control.

Phenytek

Generic Name: phenytoin

Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: n.a.

What is Phenytek?

Zovirax (Acyclovir Suspension)

Generic Name: acyclovir

Brand name: Sitavig, Zovirax

Synonyms: Zovirax

What is Zovirax (Acyclovir Suspension)?