Phenytoin Extended-Release Capsules and Plavix
Determining the interaction of Phenytoin Extended-Release Capsules and Plavix and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:In vitro studies have shown that high concentrations of clopidogrel inhibit CYP450 2C9 isoenzymes. The metabolism of drugs which are substrates for this enzyme may be decreased, potentiating toxicity of the substrate drug. The clinical significance and magnitude of this interaction is not known. Dose adjustments may be necessary if an interaction is suspected.
- "Product Information. Plavix (clopidogrel)." Bristol-Myers Squibb, Princeton, NJ.
Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Phenytoin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Phenytoin Extended-Release Capsules-Plazomicin
- Phenytoin Extended-Release Capsules-Plazomicin Intravenous
- Phenytoin Extended-Release Capsules-Plazomicin Sulfate
- Phenytoin Extended-Release Capsules-Plecanatide
- Phenytoin Extended-Release Capsules-Plegridy
- Phenytoin Extended-Release Capsules-Plegridy Pen
- Plavix-Phenytoin Infatabs
- Plavix-Phenytoin injection
- Plavix-Phenytoin Intravenous
- Plavix-Phenytoin Oral Suspension
- Plavix-Phenytoin Sodium
- Plavix-Phenytoin Sodium, Prompt injection