Phenytoin Suspension and Pro-C-Dure 5
Determining the interaction of Phenytoin Suspension and Pro-C-Dure 5 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using phenytoin together with triamcinolone can make triamcinolone less effective. Talk with your doctor before using these medications together. You may need a dose adjustment or special tests to safely take both medications. It is important that you to tell your doctor about all other medications that you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Phenytoin and other hydantoins may induce the CYP450 3A4 hepatic metabolism of corticosteroids and increase their clearance and decrease their half-lives, possibly reducing their therapeutic efficacy. In addition, results of the dexamethasone adrenal suppression test may be unreliable in patients concurrently taking phenytoin. Hydrocortisone appears to be affected to a lesser extent than other corticosteroids. Some corticosteroids have also been reported to cause increases or decreases in serum phenytoin levels; however, data have been inconsistent.
MANAGEMENT: Patients should be closely monitored for clinical and laboratory evidence of reduced corticosteroid effects and changes in phenytoin concentrations during concomitant therapy. Some patients may require increased corticosteroid dosages.
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Generic Name: phenytoin
Brand name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt
Synonyms: Phenytoin
Generic Name: triamcinolone
Brand name: Aristocort, Azmacort, Kenalog-40, Zilretta
Synonyms: Triamcinolone, Triamcinolone (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Phenytoin Suspension-Pro-C-Dure 5 Kit
- Phenytoin Suspension-Pro-C-Dure 6
- Phenytoin Suspension-Pro-C-Dure 6 Kit
- Phenytoin Suspension-Pro-Chlo
- Phenytoin Suspension-Pro-Clear AC
- Phenytoin Suspension-Pro-Fast
- Pro-C-Dure 5-Philith
- Pro-C-Dure 5-Phillips Milk of Magnesia
- Pro-C-Dure 5-Phisohex
- Pro-C-Dure 5-Phl-Fluoxetine
- Pro-C-Dure 5-Phlemex
- Pro-C-Dure 5-Phlemex Forte