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Pilocarpine Eye Drops and Theraflu Warming Relief Nighttime Severe Cold

Determining the interaction of Pilocarpine Eye Drops and Theraflu Warming Relief Nighttime Severe Cold and the possibility of their joint administration.

Check result:
Pilocarpine Eye Drops <> Theraflu Warming Relief Nighttime Severe Cold
Relevance: 17.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

DiphenhydrAMINE may reduce the effects of pilocarpine ophthalmic. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor

Professional:

MONITOR: Theoretically, anticholinergic agents and other agents with significant anticholinergic activity (e.g., antihistamines, antispasmodics, neuroleptics, phenothiazines, skeletal muscle relaxants, tricyclic antidepressants, class IA antiarrhythmics especially disopyramide) may antagonize the effects of topically administered cholinergic agents such as acetylcholine, carbachol, demecarium, echothiophate, isoflurophate, physostigmine, and pilocarpine. The proposed mechanism involves opposing pharmacodynamic action on muscarinic receptor sites in ocular tissue. This interaction is sometimes desirable and is the basis for using atropine in the treatment of excessive muscarinic side effects and cholinergic crisis induced by cholinergic overdose.

MANAGEMENT: Patients receiving long-term therapy with anticholinergic agents should be monitored for potentially diminished therapeutic (miotic) response to ophthalmic cholinergic therapy, and dosages adjusted as necessary.

References
  • "Product Information. Pilopine HS (pilocarpine ophthalmic)." Alcon Laboratories Inc, Fort Worth, TX.
  • "Multum Information Services, Inc. Expert Review Panel"
Pilocarpine Eye Drops

Generic Name: pilocarpine ophthalmic

Brand name: Pilocar, Pilopine-HS, Pilostat, Isopto Carpine, Adsorbocarpine, Pilagan with C Cap, Ocu-Carpine, Ocusert, Piloptic-1/2, Piloptic-1, Akarpine, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6

Synonyms: Pilocarpine ophthalmic, Pilocarpine (Ophthalmic)

Theraflu Warming Relief Nighttime Severe Cold

Generic Name: acetaminophen / diphenhydramine / phenylephrine

Brand name: Theraflu Warming Relief Nighttime Severe Cold, Benadryl Allergy & Sinus Headache, Delsym Cough Plus Cold Night Time, Mucinex Fast-Max Night Time Cold and Flu, Robitussin Nighttime Multi-Symptom Cold, Sudafed PE Severe Cold, Theraflu Severe Cold & Cough Nighttime, Theraflu Warming Flu & Sore Throat, Theraflu Warming Sinus & Cold, Theraflu Warming Severe Cold Nighttime, Benadryl Allergy & Cold, Sudafed PE Nighttime Cold, Tylenol Allergy Multi-Symptom Nighttime, Theraflu Nighttime Severe Cough & Cold, Children's Delsym Cough Plus Cold Night Time, Children's Mucinex Night Multi-Symp Cold, Children's Dimetapp Multi-Symptom Cold & Flu, Theraflu ExpressMax Nighttime Severe C&C, Theraflu PowerPods Nighttime Severe Cold, Benadryl Allergy/Cold, Tylenol Allergy Multi-Symptom

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.