Pilostat and Ratio-Levobunolol

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Limited data indicate that addition of pilocarpine to levobunolol eye drops significantly decreases ocular absorption of levobunolol. The ocular absorption of levobunolol is pH-dependent, and pilocarpine significantly buffers levobunolol ophthalmic solutions. At acidic pH, the ocular absorption of levobunolol in the presence of pilocarpine may be enhanced by the use of sulfosuccinates.

Pilostat

Generic Name: pilocarpine ophthalmic

Brand name: Pilocar, Pilopine-HS, Pilostat, Isopto Carpine, Adsorbocarpine, Pilagan with C Cap, Ocu-Carpine, Ocusert, Piloptic-1/2, Piloptic-1, Akarpine, Piloptic-2, Piloptic-3, Piloptic-4, Piloptic-6

Synonyms: n.a.

What is Pilostat?

Ratio-Levobunolol

Generic Name: levobunolol ophthalmic

Brand name: Betagan, Akbeta, Levobunolol, Betagan C-Cap

Synonyms: Levobunolol ophthalmic, Levobunolol

What is Ratio-Levobunolol?