Pimecrolimus Cream and Verapamil Extended Release Tablets
Determining the interaction of Pimecrolimus Cream and Verapamil Extended Release Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Theoretically, coadministration with CYP450 3A inhibitors may increase the plasma concentrations of pimecrolimus, which has been shown in vitro to undergo metabolism by this subfamily of hepatic microsomal enzymes. Although clinically significant drug interactions are not expected due to minimal systemic absorption of topically administered pimecrolimus, the possibility cannot be ruled out. The manufacturer recommends caution in patients with widespread and/or erythrodermic disease.
- "Product Information. Elidel (pimecrolimus topical)." Novartis Pharmaceuticals, East Hanover, NJ.
Generic Name: pimecrolimus topical
Brand name: Elidel
Synonyms: Pimecrolimus topical, Pimecrolimus
Generic Name: verapamil
Brand name: Calan, Isoptin SR, Verelan, Isoptin, Calan SR, Isoptin IV, Covera-HS, Verelan PM
Synonyms: Verapamil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pimecrolimus Cream-Verapamil Hydrochloride
- Pimecrolimus Cream-Verapamil Hydrochloride PM
- Pimecrolimus Cream-Verapamil Immediate-Release Tablets
- Pimecrolimus Cream-Verapamil Injection
- Pimecrolimus Cream-Verapamil Intravenous
- Pimecrolimus Cream-Verapamil Long-Acting Capsules
- Verapamil Extended Release Tablets-Pimecrolimus topical
- Verapamil Extended Release Tablets-Pimozide
- Verapamil Extended Release Tablets-Pimtrea
- Verapamil Extended Release Tablets-Pin-X
- Verapamil Extended Release Tablets-Pin-X (Pyrantel Pamoate Chewable Tablets)
- Verapamil Extended Release Tablets-Pin-X (Pyrantel Pamoate Suspension)