Pioglitazone and metformin and Wakix Tablets
Determining the interaction of Pioglitazone and metformin and Wakix Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with pitolisant may increase plasma concentrations of substrates of the hepatic and intestinal uptake transporter, organic cation transporter 1 (OCT1). Pitolisant has demonstrated inhibitory potential towards OCT1 in vitro. The clinical significance of this effect has not been established. MANAGEMENT: Caution is recommended when pitolisant is administered with OCT1 substrates. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Professional:MONITOR: Coadministration with pitolisant may increase plasma concentrations of substrates of the hepatic and intestinal uptake transporter, organic cation transporter 1 (OCT1). Pitolisant has demonstrated inhibitory potential towards OCT1 in vitro. The clinical significance of this effect has not been established.
MANAGEMENT: Caution is recommended when pitolisant is administered with OCT1 substrates.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: metformin / pioglitazone
Brand name: Actoplus Met, Actoplus Met XR
Synonyms: Metformin and pioglitazone, Pioglitazone and Metformin
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pioglitazone and metformin-Wal-Fex
- Pioglitazone and metformin-Wal-finate
- Pioglitazone and metformin-Wal-itin
- Pioglitazone and metformin-Wal-Zyr D
- Pioglitazone and metformin-Walgreens Ibuprofen Junior Strength
- Pioglitazone and metformin-Warfarin
- Wakix Tablets-Pioglitazone and Metformin Extended-Release Tablets
- Wakix Tablets-Pioglitazone and Metformin Tablets
- Wakix Tablets-Pioglitazone Hydrochloride
- Wakix Tablets-Pioglitazone Tablets
- Wakix Tablets-Piperacillin
- Wakix Tablets-Piperacillin and tazobactam