Pitolisant Hydrochloride and Premesyn PMS

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available. MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.

MONITOR: Coadministration with pitolisant may reduce plasma concentrations of substrates of CYP450 2C, P-glycoprotein (P-gp), and uridine diphosphate glucuronosyltransferases (UGTs). Based on in vitro data, pitolisant and its main metabolites may induce CYP450 2C, P-gp, and UGTs. Clinical data are not available.

MANAGEMENT: Caution is recommended if pitolisant is used in combination with substrates of CYP450 2C, P-gp, and/or UGTs. Clinical and laboratory monitoring may be appropriate for some drugs whenever pitolisant is added to or withdrawn from therapy.

Pitolisant Hydrochloride

Generic Name: pitolisant

Brand name: Wakix

Synonyms: Pitolisant

What is Pitolisant Hydrochloride?

Premesyn PMS

Generic Name: acetaminophen / pamabrom / pyrilamine

Brand name: Midol PMS Maximum Strength, Pamprin Multi-Symptom, Premesyn PMS, Pamprin ES Multi-Symptom Relief Formula, Pamprin Maximum Pain, GNP Pre-Menstrual Relief Max Strength, Menstrual Pain Relief, Menstrual PMS, Pamprin Max Pain Formula, Premsyn PMS, RA Menstrual Pain Relief

Synonyms: n.a.

What is Premesyn PMS?