Pitolisant Hydrochloride and Tofranil injection
Determining the interaction of Pitolisant Hydrochloride and Tofranil injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.
MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: pitolisant
Brand name: Wakix
Synonyms: Pitolisant
Generic Name: imipramine
Brand name: Tofranil, Tofranil-PM
Synonyms: Tofranil
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pitolisant Hydrochloride-Tofranil-PM
- Pitolisant Hydrochloride-Tol-Tab
- Pitolisant Hydrochloride-Tolazamide
- Pitolisant Hydrochloride-Tolbutamide
- Pitolisant Hydrochloride-Tolcapone
- Pitolisant Hydrochloride-Tolectin 600
- Tofranil injection-Pitressin
- Tofranil injection-Pitressin Injection
- Tofranil injection-Pitressin Synthetic
- Tofranil injection-Placidyl
- Tofranil injection-Plan B
- Tofranil injection-Plan B One-Step