Plazomicin Sulfate and Remifentanil Hydrochloride

• Generic Name: plazomicin
• Dosage Forms: n.a.
• Other Brand Names: Zemdri

Plazomicin sulfate is an aminoglycoside antibacterial indicated for the treatment of patients 18 years of age or older with complicated urinary tract Infections (cUTI), including pyelonephritis.

As only limited clinical safety and efficacy data are available, reserve plazomicin sulfate for use in patients who have limited or no alternative treatment options.

To reduce the development of drug-resistant bacteria and maintain effectiveness of plazomicin sulfate and other antibacterial drugs, plazomicin sulfate should be used only to treat infections that are proven or strongly suspected to be caused by susceptible microorganisms.

• Generic Name: remifentanil
• Dosage Forms: n.a.
• Other Brand Names: Ultiva

As the analgesic component in the induction and maintenance of general anesthesia for inpatient and outpatient procedures. Although remifentanil has been used as the primary agent for induction of anesthesia, its use as the sole agent in general anesthesia is not recommended because loss of consciousness cannot be ensured and a high incidence of apnea, muscle rigidity, or tachycardia is possible.

May be continued in the immediate postoperative period in adults for whom later transition to longer-acting analgesics is desired; must be used under direct supervision of an anesthesia clinician in a postoperative anesthesia care unit or intensive care unit (ICU). Long-term (i.e., >16 hours) use of remifentanil in ICU patients has not been established to date.

May be particularly useful in surgical procedures requiring a rapid onset of analgesia and rapid recovery.

As the analgesic component of monitored anesthesia care (e.g., in conjunction with local or regional anesthesia for surgical procedures, including ophthalmic surgery, breast biopsy, and other superficial surgical procedures ) in adults.