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Pms-Isoniazid and Pronestyl-SR

Determining the interaction of Pms-Isoniazid and Pronestyl-SR and the possibility of their joint administration.

Check result:

Pms-Isoniazid <> Pronestyl-SR

Relevance: 28.03.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Procainamide may increase the serum half-life of isoniazid by an unknown mechanism. The clinical significance of this interaction is not known. No special precautions are necessary.

References

Schneck D, Hayes A, Shiroff R, Sprouse J "Effect of procainamide and isoniazid on each other's acetylation pathway in normal subjects." Clin Pharmacol Ther 21 (1977): 116

Pms-Isoniazid

Generic Name: isoniazid

Brand name: Nydrazid

Synonyms: Isoniazid

What is Pms-Isoniazid?

Pronestyl-SR

Generic Name: procainamide

Brand name: Pronestyl, Procan SR, Pronestyl-SR, Procanbid

Synonyms: n.a.

What is Pronestyl-SR?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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