Pod-Care 100C and Xanax XR
Determining the interaction of Pod-Care 100C and Xanax XR and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Certain corticosteroids may decrease the plasma concentration of some benzodiazepines. Limited data are available for midazolam and triazolam. The mechanism is related to induction of hepatic cytochrome P450 enzymes responsible for benzodiazepine metabolism. The clinical significance may depend on the dosage and duration of corticosteroid therapy and be of greater importance with oral administration of benzodiazepines.
- Villikka K, Kivisto KT, Neuvonen PJ "The effect of dexamethasone on the pharmacokinetics of triazolam." Pharmacol Toxicol 83 (1998): 135-8
- Nakajima M, Suzuki T, Sasaki T, Yokoi T, Hosoyamada A, Yamamoto T, Kuroiwa Y "Effects of chronic administration of glucocorticoid on midazolam pharmacokinetics in humans." Ther Drug Monit 21 (1999): 507-13
Generic Name: betamethasone
Brand name: Celestone Soluspan, Celestone, Celestone Phosphate, Selestoject, Cell-U-Jec, Adbeon, Beta-Phos/AC
Synonyms: Betamethasone (injection), Betamethasone (Systemic)
Generic Name: alprazolam
Brand name: Niravam, Xanax, Xanax XR, Alprazolam Intensol
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Pod-Care 100C-Xanax XR Oral
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- Pod-Care 100C-Xarelto
- Pod-Care 100C-Xarelto Starter Pack
- Pod-Care 100C-Xartemis XR
- Pod-Care 100C-Xartemix XR
- Xanax XR-Pod-Care 100K
- Xanax XR-Podactin
- Xanax XR-Polaramine
- Xanax XR-Polatuzumab vedotin
- Xanax XR-Polatuzumab Vedotin-piiq
- Xanax XR-Polio vaccine, inactivated