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Pontocaine HCl and Rituximab and hyaluronidase human, recombinant Subcutaneous

Determining the interaction of Pontocaine HCl and Rituximab and hyaluronidase human, recombinant Subcutaneous and the possibility of their joint administration.

Check result:
Pontocaine HCl <> Rituximab and hyaluronidase human, recombinant Subcutaneous
Relevance: 22.11.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

When hyaluronidase is added to a local anesthetic, the local anesthetic solution undergoes increased absorption, resulting in a shorter duration of action and possible increased frequency of systemic reactions. The clinical significance is unknown. It may be advisable to monitor the patient for altered anesthetic efficacy and side effects.

References
  • "Product Information. Vitrase (hyaluronidase)." Bausch and Lomb, Rochester, NY.
Pontocaine HCl

Generic Name: tetracaine

Brand name: Niphanoid, Pontocaine HCl

Synonyms: n.a.

Rituximab and hyaluronidase human, recombinant Subcutaneous

Generic Name: hyaluronidase / rituximab

Brand name: Rituxan Hycela

Synonyms: Hyaluronidase and rituximab, Rituximab and Hyaluronidase

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.