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Portia-28 and Zidovudine oral/injection

Determining the interaction of Portia-28 and Zidovudine oral/injection and the possibility of their joint administration.

Check result:

Portia-28 <> Zidovudine oral/injection

Relevance: 09.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Ethinyl estradiol has been shown to inhibit the glucuronidation of zidovudine in vitro. A clinically significant interaction has not been demonstrated, however.

References

Sim SM, Back DJ, Breckenridge AM "The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes." Br J Clin Pharmacol 32 (1991): 17-21

Portia-28

Generic Name: ethinyl estradiol / levonorgestrel

Brand name: Amethyst, Aviane, Balcoltra, Falmina, Levlen, Lillow, Orsythia, Vienva, Afirmelle, Altavera, Amethia, Amethia Lo, Ashlyna, Aubra, Aubra EQ, Ayuna, Camrese, Camrese Lo, Chateal, Chateal EQ, Daysee, Delyla, Enpresse-28, FaLessa, Fayosim, Introvale, Jolessa, Kurvelo, Larissia, Lessina, Levonest, Levora 015/30, LoSeasonique, Lutera, Marlissa, Myzilra, Portia-28, Quartette, Quasense, Rivelsa, Seasonique, Setlakin, Simpesse, Sronyx, Trivora, Alesse, Enpresse, Levora, Lybrel, Nordette, Portia, Tri-Levlen, Triphasil-21, Triphasil-28, Trivora-28, Seasonale, Preven EC, Triphasil

Synonyms: Ethinyl estradiol and levonorgestrel, Ethinyl Estradiol and Levonorgestrel

What is Portia-28?

Zidovudine oral/injection

Generic Name: zidovudine

Brand name: Retrovir

Synonyms: Zidovudine (oral/injection), Zidovudine

What is Zidovudine oral/injection?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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