Potassium and Theraflu Max-D Severe Cold & Flu
Determining the interaction of Potassium and Theraflu Max-D Severe Cold & Flu and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using pseudoephedrine together with potassium citrate may increase the effects of pseudoephedrine. Contact your doctor if you experience tremor, anxiety, insomnia, irritability, or nervousness. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Alkalization of the urine decreases the urinary excretion increases the elimination half-life of ephedrine, pseudoephedrine, and related drugs. According to one report, an increase in pH from 5.1 to 7.1 increased the half-life of pseudoephedrine from 5 to 16 hours. Toxicity from long-term use of pseudoephedrine has been demonstrated in patients with persistently alkaline urine.
MANAGEMENT: Patients should be monitored for toxic effects such as tremor, anxiety, insomnia, irritability, or nervousness. Dosage reductions may be required.
- Kuntzman RG, Tsai I, Brand L, Mark LC "The influence of urinary pH on the plasma half-life of pseudoephedrine in man and dog and a sensitive assay for its determination in human plasma." Clin Pharmacol Ther 12 (1971): 62-7
- Brater DC, Kaojarern S, Benet LZ, et al "Renal excretion of pseudoephedrine." Clin Pharmacol Ther 28 (1980): 690-4
- Wilkinson GR, Beckett AH "Absorption metabolism and excretion of the ephedrines in man. I. The influence of urinary pH and urine volume output." J Pharmacol Exp Ther 162 (1968): 139-47
Generic Name: potassium citrate
Brand name: Urocit-K
Synonyms: Potassium Citrate
Generic Name: acetaminophen / dextromethorphan / guaifenesin / pseudoephedrine
Brand name: Duraflu, Robitussin Cold Cough and Flu, Theraflu Max-D Severe Cold & Flu, Sudafed Cold and Cough Liquicaps, Theraflu Chest and Cough, Tylenol Cold Severe Congestion Non-Drowsy, Sudafed Sinus and Cold Liquicaps, Phlemgesic, Maxiflu DM, Flutabs, Tylenol Cold Severe Congestion
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Potassium-Theraflu Maximum Strength
- Potassium-Theraflu Nighttime Severe Cold
- Potassium-Theraflu Nighttime Severe Cough and Cold
- Potassium-Theraflu PowerPods (Acetaminophen, Dextromethorphan, and Phenylephrine Pods)
- Potassium-Theraflu PowerPods (Acetaminophen, Diphenhydramine, and Phenylephrine Pods)
- Potassium-Theraflu Severe Cold & Congestion
- Theraflu Max-D Severe Cold & Flu-Potassium Acetate
- Theraflu Max-D Severe Cold & Flu-Potassium Acetate Concentrate
- Theraflu Max-D Severe Cold & Flu-Potassium aminobenzoate
- Theraflu Max-D Severe Cold & Flu-Potassium and sodium phosphate
- Theraflu Max-D Severe Cold & Flu-Potassium bicarbonate
- Theraflu Max-D Severe Cold & Flu-Potassium bicarbonate and potassium chloride