Pralidoxime Chloride and Zinecard

• Generic Name: pralidoxime
• Dosage Forms: Injection
• Other Brand Names: Protopam Chloride

Pralidoxime reverses muscle weakness or paralysis caused by a poison or certain drug overdose.

Pralidoxime is used as an antidote to treat poisoning by a chemical or pesticide (insect spray), or by a drug used to treat a muscle disorder.

This medication is not effective as an antidote for all types of pesticide poisonings.

Pralidoxime may also be used for purposes not listed in this medication guide.

• Generic Name: dexrazoxane
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Totect, Zinecard

Zinecard is used to protect the heart and other tissues from harmful side effects caused by certain cancer medications.

The Totect brand of dexrazoxane is used in men or women to treat a condition called extravasation (es-TRA-va-ZAY-shun). Extravasation happens when an injected medicine escapes from the blood vessels and circulates into tissues in the body. Serious tissue damage can occur when extravasation happens during injection of certain cancer medications.

The Zinecard brand of dexrazoxane is used to help prevent chemotherapy-related heart problems in women who are receiving doxorubicin for metastatic breast cancer. Zinecard is given only after you have received enough doxorubicin infusions to amount to a certain total dose.

Zinecard may also be used for purposes not listed in this medication guide.