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Pramlintide and Triactin

Determining the interaction of Pramlintide and Triactin and the possibility of their joint administration.

Check result:
Pramlintide <> Triactin
Relevance: 15.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Ask your doctor before using dicyclomine together with pramlintide. Due to its effect on stomach emptying, pramlintide should not be used in patients taking dicyclomine. Dicyclomine may also slow stomach emptying or slow the intestinal absorption of nutrients. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The use of pramlintide in combination with drugs that alter gastrointestinal motility (e.g., loperamide; anticholinergic agents) or drugs that slow the intestinal absorption of nutrients (e.g., alpha-glucosidase inhibitors) has not been studied. Because pramlintide slows gastric emptying, the potential for a pharmacodynamic interaction is possible.

MANAGEMENT: Due to its effect on gastric emptying, pramlintide therapy should not be considered for patients taking drugs that alter gastrointestinal motility or drugs that slow the intestinal absorption of nutrients.

References
  • "Product Information. Symlin (pramlintide)." Amphastar Pharmaceuticals Inc, South El Monte, CA.
Pramlintide

Generic Name: pramlintide

Brand name: SymlinPen 120, SymlinPen 60, Symlin

Synonyms: n.a.

Triactin

Generic Name: dicyclomine

Brand name: Bentyl, Dibent, Dicyclocot

Synonyms: Dicyclomine

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction