Prednisone Oral Concentrate and Sodium Bicarbonate Infant Injection
Determining the interaction of Prednisone Oral Concentrate and Sodium Bicarbonate Infant Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.
- Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
- Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
- Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Generic Name: prednisone
Brand name: Rayos, Sterapred, Deltasone
Synonyms: Prednisone, PredniSONE
Generic Name: sodium bicarbonate
Brand name: Neut
Synonyms: Sodium bicarbonate, Sodium Bicarbonate
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Prednisone Oral Concentrate-Sodium Bicarbonate Injection
- Prednisone Oral Concentrate-Sodium bicarbonate Oral, Intravenous, Subcutaneous
- Prednisone Oral Concentrate-Sodium Bicarbonate Tablets
- Prednisone Oral Concentrate-Sodium Bicarbonate, Citric Acid, and Simethicone Effervescent Granule Pkt
- Prednisone Oral Concentrate-Sodium biphosphate and sodium phosphate
- Prednisone Oral Concentrate-Sodium biphosphate and sodium phosphate rectal
- Sodium Bicarbonate Infant Injection-Prednisone Oral Solution
- Sodium Bicarbonate Infant Injection-Prednisone Tablets
- Sodium Bicarbonate Infant Injection-PreferaOB
- Sodium Bicarbonate Infant Injection-PreferaOB (Prenatal Vitamin Without Vitamin A)
- Sodium Bicarbonate Infant Injection-PreferaOB (Vitamins (Multiple/Prenatal))
- Sodium Bicarbonate Infant Injection-PreferaOB + DHA