Pretomanid Tablets and Vistaril IM

• Generic Name: pretomanid
• Dosage Forms: tablet
• Other Brand Names:

Limited Population: Pretomanid is an antimycobacterial indicated as part of a combination regimen with bedaquiline and linezolid for the treatment of adults with pulmonary extensively drug resistant (XDR), treatment-intolerant or nonresponsive multidrug-resistant (MDR) tuberculosis (TB). Approval of this indication is based on limited clinical safety and efficacy data. This drug is indicated for use in a limited and specific population of patients.

Pretomanid is not indicated for patients with: drug-sensitive (DS) tuberculosis, latent infection due to Mycobacterium tuberculosis, extrapulmonary infection due to M. tuberculosis, or MDR-TB that is not treatment-intolerant or nonresponsive to standard therapy.

Safety and effectiveness of pretomanid have not been established for its use in combination with drugs other than bedaquiline and linezolid as part of the recommended dosing regimen.

• Generic Name: hydroxyzine
• Dosage Forms: capsules and oral suspension
• Other Brand Names: Vistaril, Atarax, ANX, Vistaril IM, Hyzine, Vistaject-50, Rezine

Hydroxyzine injection is used to used to help control anxiety and tension caused by dental, nervous, and emotional conditions. It can also be used to help control anxiety and produce sleep before and after surgery. This medicine is also used to relieve symptoms of an allergic reaction (eg, hives, itching skin) caused by asthma and chronic urticaria.

Hydroxyzine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. This medicine is also used to control anxiety withdrawal symptoms in alcoholic patients. It is also used to control nausea and vomiting symptoms, and relieve anxiety in patients with certain heart disease.

This medicine is to be given by or under the supervision of your doctor.