Prevalite and Raloxifene
Determining the interaction of Prevalite and Raloxifene and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Ask your doctor before using cholestyramine together with raloxifene. Using these medications together can decrease the effects of raloxifene. Cholestyramine may bind to raloxifene in the intestines and prevent raloxifene from being utilized by the body. Take raloxifene at least 1 hour before or 4 to 6 hours after taking a dose of cholestyramine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: Cholestyramine has been shown to cause a 60% reduction in the absorption and enterohepatic recycling of raloxifene. The mechanism has not been described, but is probably due to a binding phenomenon occurring in the intestine. A similar reaction may occur with colestipol, although data is lacking.
MANAGEMENT: The manufacturer recommends that these drugs not be coadministered.
- "Product Information. Evista (raloxifene)." Lilly, Eli and Company, Indianapolis, IN.
Generic Name: cholestyramine
Brand name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Prevalite-Raloxifene Hydrochloride
- Prevalite-Raloxifene Hydrochloride Tablets
- Prevalite-Raltegravir
- Prevalite-Raltegravir Chewable Tablets
- Prevalite-Raltegravir Potassium
- Prevalite-Raltegravir Powder for Oral Suspension
- Raloxifene-Preven EC
- Raloxifene-Prevex Hc Topical application
- Raloxifene-Previfem
- Raloxifene-Prevnar
- Raloxifene-Prevnar Intramuscular
- Raloxifene-Prevpac