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Prilocaine Hydrochloride and Technetium tc 99m tilmanocept Injection

Determining the interaction of Prilocaine Hydrochloride and Technetium tc 99m tilmanocept Injection and the possibility of their joint administration.

Check result:
Prilocaine Hydrochloride <> Technetium tc 99m tilmanocept Injection
Relevance: 21.10.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Tilmanocept should not be mixed or coadministered with prilocaine or other local anesthetics due to potential impairment of lymph nodal mapping.

Professional:

GENERALLY AVOID: Locally injected anesthetics have been reported to reduce lymphatic flow of Technetium Tc 99m tilmanocept in animal studies.

MANAGEMENT: Co-injection (mixture) of local anesthetics with Technetium Tc 99m tilmanocept is not recommended due to potential impairment of lymph nodal mapping.

References
  • "Product Information. Lymphoseek (tilmanocept)." Navidea Biopharmaceuticals, Dublin, OH.
Prilocaine Hydrochloride

Generic Name: prilocaine

Brand name: Citanest Plain Dental

Synonyms: Prilocaine

Technetium tc 99m tilmanocept Injection

Generic Name: tilmanocept

Brand name:

Synonyms: Technetium tc 99m tilmanocept (Injection)

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.