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Probenecid and colchicine and Tamiflu (Oseltamivir Capsules)

Determining the interaction of Probenecid and colchicine and Tamiflu (Oseltamivir Capsules) and the possibility of their joint administration.

Check result:

Probenecid and colchicine <> Tamiflu (Oseltamivir Capsules)

Relevance: 18.11.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Use of probenecid may result in significantly decreased plasma clearance and significantly increased plasma levels of oseltamivir. Probenecid decreases the renal tubular secretion of oseltamivir. Dosage adjustments of oseltamivir are typically not required due to the large safety margin of oseltamivir.

References

"Product Information. Tamiflu (oseltamivir)" RocheLaboratories, Nutley, NJ.

Probenecid and colchicine

Generic Name: colchicine / probenecid

Brand name:

Synonyms: Probenecid and colchicine (Oral)

What is Probenecid and colchicine?

Tamiflu (Oseltamivir Capsules)

Generic Name: oseltamivir

Brand name: Tamiflu

Synonyms: Tamiflu

What is Tamiflu (Oseltamivir Capsules)?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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