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Probenecid Tablets and Thiopental

Determining the interaction of Probenecid Tablets and Thiopental and the possibility of their joint administration.

Check result:

Probenecid Tablets <> Thiopental

Relevance: 19.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Probenecid may prolong the anesthesia induced by thiopental. The mechanism is unknown. Because thiopental has a short half-life, no precautions other than those routinely observed for thiopental appear to be necessary.

References

McMurray TJ, Dundee JW, Henshaw JS "The influence of probenecid on the induction dose of thiopentone." Br J Clin Pharmacol 17 (1984): p224

Probenecid Tablets

Generic Name: probenecid

Brand name: Benemid

Synonyms: Probenecid

What is Probenecid Tablets?

Thiopental

Generic Name: thiopental

Brand name:

Synonyms: n.a.

What is Thiopental?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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