Procarbazine Hydrochloride and Thiothixene

• Generic Name: procarbazine
• Dosage Forms: n.a.
• Other Brand Names: Matulane

Treatment of stage III and IV Hodgkin’s disease.

Used in various combination therapy regimens; comparative efficacy continually being evaluated.

Used in combination with mechlorethamine, vincristine, and prednisone (known as the MOPP regimen) in an alternating schedule with the ABVD regimen (doxorubicin, bleomycin, vinblastine, and dacarbazine) for treatment of Hodgkin’s disease.

Used in combination with bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, and prednisone (increased-dose BEACOPP regimen) for treatment of advanced Hodgkin’s disease.

Use in other combination regimens for treatment of advanced Hodgkin’s disease being investigated.

Treatment of brain tumors.

Used in combination with lomustine and vincristine (PCV) as adjuvant therapy following surgery and radiation therapy for malignant gliomas (e.g., anaplastic astrocytoma, glioblastoma multiforme, anaplastic oligodendroglioma).

Has been used as a component of combination chemotherapy regimens for treatment of intermediate-grade non-Hodgkin’s lymphomas.

• Generic Name: thiothixene
• Dosage Forms: n.a.
• Other Brand Names: Navane

Thiothixene is an antipsychotic medication. It affects the actions of chemicals in your brain.

Thiothixene is used to treat schizophrenia.

Thiothixene may also be used for purposes not listed in this medication guide.