Procarbazine Hydrochloride and Tricosal

• Generic Name: procarbazine
• Dosage Forms: n.a.
• Other Brand Names: Matulane

Treatment of stage III and IV Hodgkin’s disease.

Used in various combination therapy regimens; comparative efficacy continually being evaluated.

Used in combination with mechlorethamine, vincristine, and prednisone (known as the MOPP regimen) in an alternating schedule with the ABVD regimen (doxorubicin, bleomycin, vinblastine, and dacarbazine) for treatment of Hodgkin’s disease.

Used in combination with bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, and prednisone (increased-dose BEACOPP regimen) for treatment of advanced Hodgkin’s disease.

Use in other combination regimens for treatment of advanced Hodgkin’s disease being investigated.

Treatment of brain tumors.

Used in combination with lomustine and vincristine (PCV) as adjuvant therapy following surgery and radiation therapy for malignant gliomas (e.g., anaplastic astrocytoma, glioblastoma multiforme, anaplastic oligodendroglioma).

Has been used as a component of combination chemotherapy regimens for treatment of intermediate-grade non-Hodgkin’s lymphomas.

• Generic Name: choline salicylate / magnesium salicylate
• Dosage Forms: n.a.
• Other Brand Names: Choline magnesium trisalicylate, Tricosal, Trilisate, CMT

Tricosal is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain, fever, and inflammation.

Tricosal is used to treat mild-to-moderate pain, fever, inflammatory conditions, and pain, swelling, or stiffness associated with arthritis. Tricosal is also used to reduce fever in adults.

Tricosal may also be used for purposes not listed in this medication guide.