Prochieve (Progesterone Vaginal 8% Gel) and Telaprevir
Determining the interaction of Prochieve (Progesterone Vaginal 8% Gel) and Telaprevir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Telaprevir may increase the blood levels and effects of progesterone. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with telaprevir may increase the plasma concentrations of drugs that are metabolized by CYP450 3A4. The mechanism is decreased clearance due to inhibition of CYP450 3A4 activity by telaprevir.
MANAGEMENT: Caution is advised if telaprevir must be used concomitantly with medications that undergo metabolism by CYP450 3A4, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever telaprevir is added to or withdrawn from therapy.
- "Product Information. Incivek (telaprevir)." Vertex Pharmaceuticals, Cambridge, MA.
Generic Name: progesterone
Brand name: Crinone, Endometrin, FIRST-Progesterone VGS 200, Prochieve, First Progesterone MC10, Menopause Formula Progesterone, Prometrium
Synonyms: Prochieve
Generic Name: telaprevir
Brand name: Incivek
Synonyms: Telaprevir (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Prochieve (Progesterone Vaginal 8% Gel)-Telavancin
- Prochieve (Progesterone Vaginal 8% Gel)-Telavancin Hydrochloride
- Prochieve (Progesterone Vaginal 8% Gel)-Telavancin Intravenous
- Prochieve (Progesterone Vaginal 8% Gel)-Telbivudine
- Prochieve (Progesterone Vaginal 8% Gel)-Telbivudine Tablets
- Prochieve (Progesterone Vaginal 8% Gel)-Telithromycin
- Telaprevir-Prochlorperazine
- Telaprevir-Prochlorperazine Edisylate
- Telaprevir-Prochlorperazine Injection
- Telaprevir-Prochlorperazine Maleate
- Telaprevir-Prochlorperazine rectal
- Telaprevir-Prochlorperazine Suppositories