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Proleukin and RenoCal-76

Determining the interaction of Proleukin and RenoCal-76 and the possibility of their joint administration.

Check result:
Proleukin <> RenoCal-76
Relevance: 15.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using aldesleukin together with diatrizoate can lead to an increase in side effects. Symptoms generally happen within 1 to 4 hours after the administration of diatrizoate and may include nausea, vomiting, diarrhea, fever, chills, flu-like symptoms, joint pain, rash, itching, low blood pressure, and swelling. Talk to your doctor before using these medications together. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: An increased incidence (12.6%) of acute, atypical reactions to iodinated contrast media has been observed in patients who have been previously treated with interleukin-2. The cause and mechanism have not been established. Symptoms generally have an onset of 1 to 4 hours and may include nausea, vomiting, diarrhea, fever, chills, flu-like symptoms, joint pain, rash, pruritus, hypotension, edema, and oliguria. Reactions have typically been reported when patients received iodinated contrast media within 4 weeks after the last dose of interleukin-2, but have also occurred several months after interleukin treatment.

MANAGEMENT: Patients should be monitored for adverse reactions after receiving iodinated contrast media, and symptomatic treatment initiated as clinically appropriate.

References
  • "Product Information. Proleukin (aldesleukin)." Chiron Therapeutics, Emeryville, CA.
  • "Product Information. Ultravist (iopromide)." Berlex, Richmond, CA.
Proleukin

Generic Name: aldesleukin

Brand name: Proleukin

Synonyms: n.a.

RenoCal-76

Generic Name: diatrizoate

Brand name: Cystografin, Cystografin-Dilute, Gastrografin, MD-76 R, MD-Gastroview

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction