Prolixin Oral Concentrate and Zoledronic Acid Injection

• Generic Name: fluphenazine
• Dosage Forms: Tablets USP and Elixir USP, Oral Concentrate
• Other Brand Names: Permitil, Prolixin, Prolixin Decanoate, Prolixin Enanthate

Prolia (denosumab) is a monoclonal antibody. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.

The Prolia brand of denosumab is used to treat osteoporosis in postmenopausal women who have high risk of bone fracture.

Prolia is used to increase bone mass in men with osteoporosis with a high risk of bone fracture, and in women and men with a high risk of bone fracture caused by receiving treatments for certain types of cancer.

Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture.

• Generic Name: zoledronic acid
• Dosage Forms: injection
• Other Brand Names: Reclast, Zometa, Zometa Concentrate, Aclasta

Zoledronic acid (sometimes called zoledronate) is a bisphosphonate (bis FOS fo nayt) medicine that alters bone formation and breakdown in the body. This can slow bone loss and may help prevent bone fractures.

Reclast and Zometa are two different brands of zoledronic acid.

Reclast is used to treat osteoporosis caused by menopause, steroid use, or gonadal failure. zoledronic acid is for use when you have a high risk of bone fracture due to osteoporosis. Reclast is also used to treat Paget's disease of bone.

Zometa is used to treat high blood levels of calcium caused by cancer (also called hypercalcemia of malignancy). Zometa also treats multiple myeloma (a type of bone marrow cancer) or bone cancer that has spread from elsewhere in the body.

You should not use Reclast and Zometa at the same time.

Zoledronic acid may also be used for purposes not listed in this medication guide.