Promacta (Eltrombopag Powder for Suspension) and Suprep Bowel Prep

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this interaction is not currently available.ADJUST DOSING INTERVAL: Products containing aluminum, calcium, iron, magnesium, zinc and other polyvalent cations such as antacids or mineral supplements can significantly reduce the gastrointestinal absorption of eltrombopag due to chelation. In one clinical trial, administration of a single 75 mg dose of eltrombopag with an antacid containing 1524 mg aluminum hydroxide and 1425 mg magnesium carbonate resulted in an approximately 70% decrease in eltrombopag peak plasma concentration (Cmax) and systemic exposure (AUC). MANAGEMENT: Eltrombopag should be taken on an empty stomach at least 2 hours before or 4 hours after oral medications that contain antacids (e.g., didanosine buffered tablets or pediatric oral solution), aluminum, calcium, iron, magnesium, zinc or other polyvalent cations. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Promacta (eltrombopag)." GlaxoSmithKline, Research Triangle Park, NC.

ADJUST DOSING INTERVAL: Products containing aluminum, calcium, iron, magnesium, zinc and other polyvalent cations such as antacids or mineral supplements can significantly reduce the gastrointestinal absorption of eltrombopag due to chelation. In one clinical trial, administration of a single 75 mg dose of eltrombopag with an antacid containing 1524 mg aluminum hydroxide and 1425 mg magnesium carbonate resulted in an approximately 70% decrease in eltrombopag peak plasma concentration (Cmax) and systemic exposure (AUC).

MANAGEMENT: Eltrombopag should be taken on an empty stomach at least 2 hours before or 4 hours after oral medications that contain antacids (e.g., didanosine buffered tablets or pediatric oral solution), aluminum, calcium, iron, magnesium, zinc or other polyvalent cations.

Promacta (Eltrombopag Powder for Suspension)

Generic Name: eltrombopag

Brand name: Promacta

Synonyms: Promacta

What is Promacta (Eltrombopag Powder for Suspension)?

Suprep Bowel Prep

Generic Name: magnesium sulfate / potassium sulfate / sodium sulfate

Brand name: Suprep Bowel Prep Kit

Synonyms: Suprep Bowel Prep Kit

What is Suprep Bowel Prep?