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Propulsid (Cisapride Tablets) and Zileuton Tablets

Determining the interaction of Propulsid (Cisapride Tablets) and Zileuton Tablets and the possibility of their joint administration.

Check result:

Propulsid (Cisapride Tablets) <> Zileuton Tablets

Relevance: 16.09.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Cisapride is no longer on the market in the US. Do not take cisapride with any other medication.

Professional:

GENERALLY AVOID: Zileuton is believed to be a weak inhibitor of CYP450 3A4 enzymes, of which cisapride is a known substrate.

MANAGEMENT: Although no studies have been conducted to verify or quantify the interaction, caution is recommended when using this combination until further data is available.

References

"Product Information. Zylo Filmtab (zileuton)." Abbott Pharmaceutical, Abbott Park, IL.

Propulsid (Cisapride Tablets)

Generic Name: cisapride

Brand name: Propulsid

Synonyms: Propulsid (Suspension), Propulsid

What is Propulsid (Cisapride Tablets)?

Zileuton Tablets

Generic Name: zileuton

Brand name: Zyflo, Zyflo CR

Synonyms: Zileuton

What is Zileuton Tablets?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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