Propylthiouracil and Truxophyllin

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using propylthiouracil together with theophylline can alter the effects of propylthiouracil. Propylthiouracil levels should be closely monitored when theophylline is added, stopped, or the dosage is changed. You should contact your doctor if you experience nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, or an irregular heartbeat. You may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Clearance of theophylline and related agents depends upon thyroid function. In the hyperthyroid state, clearance may be enhanced. In the hypothyroid state, clearance may be reduced. Theophylline clearance may decrease and the risk of toxicity may increase when hyperthyroid patients become euthyroid.

MANAGEMENT: The patient and theophylline levels should be closely monitored while achieving a euthyroid state and when an antithyroid agent is added, discontinued, or the dosage is changed. Theophylline dosage adjustments may be required. Patients should be advised to notify their physician if they experience a worsening of their respiratory symptoms, or any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, seizures, or irregular heartbeats.

Propylthiouracil

Generic Name: propylthiouracil

Brand name:

Synonyms: n.a.

What is Propylthiouracil?

Truxophyllin

Generic Name: theophylline

Brand name: Elixophyllin, Theo-24, Respbid, T-Phyl, Aerolate III, Slo-Bid Gyrocaps, Slo-Phyllin, Theobid, Theo-Dur, Theolair, Theovent, Bronkodyl, Theo-X, Theo-Time, Theochron, Slo-Phyllin 125, Theoclear LA-130, Aerolate JR, Theolair-SR, Theoclear LA-260, Quibron-T, Quibron-T/SR, Uniphyl, Uni-Dur, Aerolate SR, Slo-Phyllin 80, Theoclear-80, Theo-Dur Sprinkles, Theosol-80, Asmalix, Aquaphyllin, Truxophyllin, Slo-Phyllin 250, TheoCap

Synonyms: Truxophyllin (Oral)

What is Truxophyllin?