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ProstaScint and Zoladex

Determining the interaction of ProstaScint and Zoladex and the possibility of their joint administration.

Check result:
ProstaScint <> Zoladex
Relevance: 19.07.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before you undergo any imaging procedure where capromab pendetide may be used, let your doctor know if you have been treated with goserelin. There is some concern that treatment with medications like goserelin that suppress the production or action of androgen may interfere with the imaging results. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The effect of surgical and/or medical androgen ablation on the imaging performance of Indium In 111 capromab pendetide has not been evaluated. Preliminary data suggest that hormone ablation may increase expression of Prostate Specific Membrane Antigen (PSMA)--the target of capromab pendetide--and decrease tumor expression of prostate specific antigen (PSA).

MANAGEMENT: Until more data are available, concomitant use of Indium In 111 capromab pendetide in patients treated with androgen ablation therapy is not recommended.

References
  • "Product Information. ProstaScint (capromab pendetide)." Aytu BioScience, Inc, Englewood, CO.
ProstaScint

Generic Name: capromab pendetide

Brand name:

Synonyms: n.a.

Zoladex

Generic Name: goserelin

Brand name: Zoladex

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction