Provayblue injection and Ziconotide Intrathecal

• Generic Name: methylene blue
• Dosage Forms: injection
• Other Brand Names: ProvayBlue, Urolene Blue

Methemoglobin is a form of hemoglobin (HEEM o glo bin). Hemoglobin is a substance in blood that carries oxygen and distributes it to your tissues and organs. However, methemoglobin is not a type of hemoglobin that is useful in carrying oxygen.

Methemoglobin normally exists in small amounts in the blood. However, when methemoglobin levels increase, the blood is less efficient in circulating oxygen. The resulting lack of oxygen throughout the body can cause symptoms such as pale or blue-colored skin.

Methemoglobinemia is a condition in which methemoglobin is present in high levels in the blood. Methemoglobinemia can occur when a person is exposed to certain drugs or chemicals such as nitrites.

Provayblue is used to treat methemoglobinemia. Provayblue works by converting methemoglobin to a more efficient type of hemoglobin to better carry oxygen throughout the body.

Provayblue may also be used for purposes not listed in this medication guide.

• Generic Name: ziconotide
• Dosage Forms: n.a.
• Other Brand Names: Prialt

Ziconotide injection is used to relieve severe chronic pain in patients who have already been treated with other medicines (e.g., morphine) and did not work well.

Ziconotide is to be given only by or under the direct supervision of a doctor.