Provera and Trastuzumab-dkst Intravenous

• Generic Name: medroxyprogesterone
• Dosage Forms: tablet
• Other Brand Names: Provera, Depo-Provera, Depo-subQ provera 104, Depo-Provera Contraceptive

Provera is a progestin (a form of progesterone), a female hormone that helps regulate ovulation (the release of an egg from an ovary) and menstrual periods.

Provera is used to treat conditions such as absent or irregular menstrual periods, or abnormal uterine bleeding. This medicine is also used to decrease the risk of endometrial hyperplasia (a condition that may lead to uterine cancer) while taking estrogens.

Provera is also used to prevent overgrowth in the lining of the uterus in postmenopausal women who are receiving estrogen hormone replacement therapy.

Provera may also be used for purposes not listed in this medication guide.

• Generic Name: trastuzumab
• Dosage Forms: n.a.
• Other Brand Names: Herceptin, Kanjinti, Ogivri

Trastuzumab-dkst injection is used alone or together with other cancer medicines (eg, carboplatin, cyclophosphamide, docetaxel, doxorubicin, paclitaxel) to treat HER2-overexpressing new or metastatic (cancer that has spread) breast cancer.

Trastuzumab-dkst injection is also used in combination with cisplatin and capecitabine or 5-fluorouracil to treat HER2-overexpressing metastatic (cancer that has spread) stomach and gastroesophageal (stomach and esophagus) cancer.

Trastuzumab-dkst prevents the growth of some tumors that produce extra amounts of a certain substance known as the HER2 protein. It should only be used in patients whose tumors have been shown to produce extra amounts of this protein (HER2 overexpression).

Trastuzumab-dkst is a monoclonal antibody. It interferes with the growth of cancer cells, which are eventually destroyed by the body. Since the growth of normal body cells may also be affected by trastuzumab-dkst, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects, such as a skin rash, may not be serious but may cause concern. Some effects do not occur until months or years after the medicine is used.

Trastuzumab-dkst is to be given only by or under the immediate supervision of your doctor.