Prudoxin Topical and Tacrolimus Oral, Intravenous

• Generic Name: doxepin topical
• Dosage Forms: cream
• Other Brand Names: Prudoxin, Zonalon

Topical doxepin is used to relieve itching in patients with certain types of eczema. It appears to work by preventing the effects of histamine, which is a substance produced by the body that causes itching.

Doxepin is available only with your doctor's prescription.

• Generic Name: tacrolimus
• Dosage Forms: n.a.
• Other Brand Names: Astagraf XL, Envarsus XR, Prograf, Hecoria

Tacrolimus is used together with other medicines to prevent the body from rejecting a transplanted organ (eg, kidney, liver, or heart). Tacrolimus may be used with steroids, azathioprine, basiliximab, or mycophenolate mofetil. Tacrolimus belongs to a group of medicines known as immunosuppressive agents.

When a patient receives an organ transplant, the body's white blood cells will try to get rid of (reject) the transplanted organ. Tacrolimus works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ.

Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections. You and your doctor should talk about the benefits of tacrolimus as well as the risks of using it.

Tacrolimus is available only with your doctor's prescription.