Pseudoephedrine and Ibuprofen Capsules and Tablets and Venastat
Determining the interaction of Pseudoephedrine and Ibuprofen Capsules and Tablets and Venastat and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using horse chestnut together with ibuprofen. Combining these medications may increase the risk of bleeding. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: When administered systemically, horse chestnut may theoretically potentiate the effects of anticoagulants, platelet inhibitors and other agents that affect hemostasis, possibly increasing the risk of bleeding and bruising. Horse chestnut contains the coumarin glycosides aesculetin, fraxin, and scopolin.
MANAGEMENT: Patients should consult a healthcare provider before taking any herbal or alternative medicine. Until more information is available, consumption of horse chestnut should preferably be avoided during use of anticoagulants, platelet inhibitors, or other agents that can cause bleeding. In patients who have used horse chestnut extensively prior to receiving these agents, the potential for an interaction should be considered. Close clinical and laboratory monitoring for bleeding complications is recommended. Patients should be advised to promptly report any signs of unusual bleeding or bruising to their physician, including pain, swelling, headache, dizziness, weakness, nosebleeds, prolonged bleeding from cuts, bleeding of gums from brushing, red or brown urine, and red or black stools.
- Heck AM, DeWitt BA, Lukes AL "Potential interactions between alternative therapies and warfarin." Am J Health Syst Pharm 57 (2000): 1221-7; quiz 1228-30
- "Product Information. Coumadin (warfarin)." DuPont Pharmaceuticals, Wilmington, DE.
- Therapeutic Research Faculty "Natural Medicines Comprehensive Database. Available from: URL: http://www.naturaldatabase.com." ([1995-2008...]):
Generic Name: ibuprofen / pseudoephedrine
Brand name: Advil Cold & Sinus, Advil Cold and Sinus Liqui-Gel, Dimetapp Sinus, Dristan Sinus, Motrin IB Sinus, Sine-Aid IB, Dayquil Pressure and Pain Caplet, Motrin Cold and Flu, Motrin Childrens Cold, Motrin Sinus Headache, Dimetapp Childrens Cold & Fever, Children's Ibuprofen Cold Relief
Synonyms: Ibuprofen and pseudoephedrine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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